Conclusions: HR-informed closed-loop control can be implemented in a portable artificial pancreas.

This model represents another step toward the development of a bihormonal artificial pancreas.

But several trials and another one just beginning are putting the artificial pancreas within reach.

Larger studies are needed to confirm the safety and effectiveness of the new artificial pancreas app.

In 2015 DreaMed licensed its artificial pancreas technology for integration into insulin pumps made by Medtronic Diabetes.